Duloxetine (Cymbalta) is a moderately priced drug used to treat depression, anxiety, fibromyalgia, and nerve pain associated with diabetes (diabetic peripheral neuropathy). This will pass, it's only temporary. Depression is a listed mental disorder which includes altered mood; it may occur daily associated with diminished interest or pleasure in most or all of the activities. Duloxetine, sold under the brand name Cymbalta among others, is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain. It is taken by mouth. Cymbalta (duloxetine), a drug prescribed for neuropathic pain associated with diabetic peripheral neuropathy, depression, and anxiety. Side effect, dosage, and drug interaction information included. Anxiety disorders and depression are treatable. Many people experience meaningful symptom relief and improvement in their quality of life with professional care. However, treatment success varies. Some people respond to treatment after a few weeks or months while others may take longer. If people have more than one anxiety disorder or if they. User Reviews for Cymbalta to treat Depression. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Serotonin Supplements to Treat Depression, Anxiety, and Insomnia Yourself Feeling pessimistic, sad, panicky, or irritable? Can’t sleep? Here's how to use four powerful, research-proven serotonin supplements for depression and anxiety. A person's dosage of Cymbalta is often determined by the medical condition being treated and existing medical conditions, among other things. The recommended starting dose for treating neuropathic pain or generalized anxiety disorder is 60 mg once daily. I've been taking Cymbalta for about a month because the Lexapro was horrible for me. I think it made me feel worse rather than better. I did notice in the first week Cymbalta made me sleepy but I'm fine now and it really does help my depression and anxiety. Cymbalta Side Effects: An Introduction As with any medicine, there are possible side effects with Cymbalta ® (duloxetine hydrochloride). However, not everyone who takes Cymbalta will experience side effects.